Description
CD160 antigen is also known as natural killer cell receptor BY55, is a 27 kDa glycoprotein, contains 1 Ig-like V-type (immunoglobulin-like) domain.
Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity.
CD160 is expressed at the cell surface as a tightly disulfide-linked multimer.
In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes.
CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.
When expressed on vascular endothelial cells, CD160 propagates anti-angiogenic signals and promotes apoptosis